be in charge of, manage, oversee
我是管不好但我能掌管曼哈顿计划
I’m not good at managing things, but I can take charge of the Manhattan Project.
— 奥本海默 (2023)
他想让我早点去他公司掌管财务
He wants me to join his company early and take charge of the finances.
— 女王旅途 (2014)